TECNATOX. Center for Environmental, Food and Toxicological Technology

HEALTH AND THE ENVIRONMENT
TARGETS

The Center for Environmental, Food, and Toxicological Technology (TecnATox) was born in 2008 as a result of the merger of members of the group of the Laboratory of Toxicology and Environmental Health (LTSM) and the groups of Environmental Analysis and Management (AGA, later AGACAPE ) and Research in Neurobehavior and Health (NEUROLAB). Recently, the group Mathematical Models for Environmental and Biomedical Engineering (MMEAB) has also joined. All four groups, from the Universitat Rovira i Virgili, are research groups consolidated by the Agency for the Management of University and Research Grants (AGAUR). TecnATox aims to carry out research and development in the field of environmental and food protection at the European level, as well as to satisfy, from the University, the needs of the administration and the productive sectors, utilizing actions of knowledge and technology. TecnATox provides its customers with high-quality products and scientific-technical rigor.

RESPONSIBLE
  • Josep Lluís Domingo

  • Marta Schuhmacher

  • Presentation
  • Lines
  • Group members
  • Publications
  • Projects
  • Contact

TecnATox carries out its research and development activities in the field of environmental protection and human health, satisfying from the university level the technological needs of different productive sectors and the administration through development actions. and knowledge transfer in the newest aspects of environmental management and health.

Maximum professionalism and confidentiality are guaranteed in all actions, information, and achievements.

  • Toxicology
  • Health risk assessment
  • Food toxicology
  • Neurotoxicology, neurobehavior and neuropsychology
  • Radiobiology
  • Ecotoxicology
  • Environmental computing and systems toxicology
  • Neuropsychology and emotions

    Year

    APOE genotype andpostnatal chlorpyrifos exposure modulate gut microbiota and cerebral short-chain fatty acids in preweaning mice

    Guardia-Escote L, Basaure P, Biosca-Brull J, Cabré M, Blanco J,Pérez-Fernández C, Sánchez-Santed F, Domingo JL, Colomina MT

    Food Chem Toxicol

    2020 Jan;135:110872

    10.1016/j.fct.2019.110872

    Air quality, health impacts and burden of disease due to air pollution (PM(10), PM(25), NO(2) and O(3)): Application ofAirQ+ model to the Camp de Tarragona County (Catalonia, Spain)

    Rovira J, Domingo JL, Schuhmacher M

    Sci TotalEnviron

    2020 Feb 10;703:135538

    10.1016/j.scitotenv.2019.135538

    Mercury speciation in preserved historical sludge: Potential risk from sludge containedwithin reclaimed land ofMinamata Bay, Japan

    Sakamoto M, Itai T, Marumoto K, Marumoto M, Kodamatani H, Tomiyasu T,Nagasaka H, Mori K, Poulain AJ, Domingo JL, Horvat M, Matsuyama A

    Environ Res

    2020 Jan;180:108668

    10.1016/j.envres.2019.108668

    Multi-box mass balance model of PFOA and PFOS in different regions of San Francisco Bay

    Sánchez-Soberón F, Sutton R, Sedlak M, Yee D, Schuhmacher M, Park JS.
    Chemosphere. 2020 Aug;252:126454.
    DOI: 10.1016/j.chemosphere.2020.126454

     

    An integrative translational framework for chemical induced neurotoxicity - a systematic review

    Deepika D, Sharma RP, Schuhmacher M, Kumar V.
    Crit Rev Toxicol. 2020 May;50(5):424-438.
    DOI: 10.1080/10408444.2020.1763253

     

     

    Biomonitoring of co-exposure to bisphenols by consumers of canned foodstuffs

    González N, Marquès M, Cunha SC, Fernandes JO, Domingo JL, Nadal M.
    Environ Int. 2020 Jul;140:105760.
    DOI: 10.1016/j.envint.2020.105760

     

    Adverse health effects for populations living near waste incinerators with special attention to hazardous waste incinerators. A review of the scientific literature

    Domingo JL, Marquès M, Mari M, Schuhmacher M.
    Environ Res. 2020 Aug;187:109631.
    DOI: 10.1016/j.envres.2020.109631

     

    Changes of organochlorine compound concentrations in maternal serum during pregnancy and comparison to serum cord blood composition

    Junqué E, Garcia S, Martínez MÁ, Rovira J, Schuhmacher M, Grimalt JO.
    Environ Res. 2020 Mar;182:108994.
    DOI: 10.1016/j.envres.2019.108994.

     

    Effects of air pollutants on the transmission and severity of respiratory viral infections
    Essential and toxic elements in human milk concentrate with human milk lyophilizate: A preclinical study
    Health risks for the population living near petrochemical industrial complexes. 1. Cancer risks: A review of the scientific literature
    Human biomonitoring to evaluate exposure to toxic and essential trace elements during pregnancy. Part B: Predictors of exposure
    Human exposure to trace elements, aromatic amines and formaldehyde in swimsuits: Assessment of the health risks
    Organophosphate metabolite concentrations in maternal urine during pregnancy
    Reconstruction of phthalate exposure and DINCH metabolites from biomonitoring data from the EXHES cohort of Tarragona, Spain: A case study on estimated vs reconstructed DEHP using the PBPK model
    Human exposure to synthetic endocrine disrupting chemicals (S-EDCs) is generally negligible as compared to natural compounds with higher or comparable endocrine activity. How to evaluate the risk of the S-EDCs?
    A systems toxicology approach to compare the heavy metal mixtures (Pb, As, MeHg) impact in neurodegenerative diseases
    Bisphenol A analogues (BPS and BPF) present a greater obesogenic capacity in 3T3-L1 cell line
    Concentrations of nine bisphenol analogues in food purchased from Catalonia (Spain): Comparison of canned and non-canned foodstuffs
    Consumers' acceptance of an online tool with personalized health risk-benefit communication about seafood consumption
    Dietary exposure to total and inorganic arsenic via rice and rice-based products consumption
    Maternal exposure to mixtures of dienestrol, linuron and flutamide. Part I: Feminization effects on male rat offspring
    Maternal exposure to mixtures of dienestrol, linuron and flutamide. Part II: Endocrine-related gene expression assessment on male offspring rat testes
    Obesogenic effects of chlorpyrifos and its metabolites during the differentiation of 3T3-L1 preadipocytes
    Comparison of aggregated exposure to di(2-ethylhexyl) phthalate from diet and personal care products with urinary concentrations of metabolites using a PBPK model - Results from the Norwegian biomonitoring study in EuroMix
    Hepatotoxicity of the pesticides imazalil, thiacloprid and clothianidin - Individual and mixture effects in a 28-day study in female Wistar rats
    Test and Risk Assessment Strategies for combined exposure to multiple chemicals
    Cumulative dietary risk assessment overarching different regulatory silos using a margin of exposure approach: A case study with three chemical silos
    Human exposure to synthetic endocrine disrupting chemicals (S-EDCs) is generally negligible as compared to natural compounds with higher or comparable endocrine activity. How to evaluate the risk of the S-EDCs?
    Corrigendum to 'Meat consumption: Which are the current global risks? A review of recent (2010-2020) evidences'. [Food Res. Int. 137 (2020) 109341]
    Meat consumption: Which are the current global risks? A review of recent (2010-2020) evidences
    Health risks for the population living near petrochemical industrial complexes. 2. Adverse health outcomes other than cancer
    Human exposure to trace elements and PCDD/Fs around a hazardous waste landfill in Catalonia (Spain)
    Human exposure to synthetic endocrine disrupting chemicals (S-EDCs) is generally negligible as compared to natural compounds with higher or comparable endocrine activity. How to evaluate the risk of the S-EDCs?
    Biomonitoring of Trace Elements in Subjects Living Near a Hazardous Waste Incinerator: Concentrations in Autopsy Tissues
    Trends of Polychlorinated Compounds in the Surroundings of a Municipal Solid Waste Incinerator in Mataró (Catalonia, Spain): Assessing Health Risks
    Improvement of APOE4-dependent non-cognitive behavioural traits by postnatal cholinergic stimulation in female mice
    Trace Elements in Blood of the Population Living near a Hazardous Waste Incinerator in Catalonia, Spain
    Sex and Exposure to Postnatal Chlorpyrifos Influence the Epigenetics of Feeding-Related Genes in a Transgenic APOE Mouse Model: Long-Term Implications on Body Weight after a High-Fat Diet
    The Roses Ocean and Human Health Chair: A New Way to Engage the Public in Oceans and Human Health Challenges
    Fully Automated Breast Density Segmentation and Classification Using Deep Learning
    Learning, memory and the expression of cholinergiccomponents in mice are modulated by the pesticide chlorpyrifos depending upon ageat exposure and apolipoprotein E (APOE) genotype

    Basaure P, Guardia-Escote L, Cabré M, Peris-Sampedro F, Sánchez-Santed F,Domingo JL, Colomina MT

    Arch Toxicol

    2019Mar;93(3):693-707

    10.1007/s00204-019-02387-9

    Characterization and risk assessment of total suspended particles (TSP) and fine particles (PM(2 5)) in a rural transformational e-waste recycling region ofSouthern China

    Wang T, Rovira J, Sierra J, Chen SJ, Mai BX, Schuhmacher M, Domingo JL

    Sci Total Environ

    2019 Nov 20;692:432-440

    10.1016/j.scitotenv.2019.07.271

    PubMed PMID: 31351287

    Combining monitoring and modelling approaches for BaP characterization over apetrochemical area

    Domínguez-Morueco N, Ratola N, Sierra J, Nadal M, Jiménez-Guerrero P

    Sci Total Environ

    2019 Mar 25;658:424-438

    10.1016/j.scitotenv.2018.12.202

    PubMed PMID: 30579200

    Changes of organochlorine compound concentrations in maternal serum duringpregnancy and comparison to serum cord blood composition

    Junqué E, Garcia S, Martínez MÁ, Rovira J, Schuhmacher M, Grimalt JO

    Environ Res

    2019 Dec3;182:108994

    10.1016/j.envres.2019.108994

    Organophosphate metabolite concentrations in maternal urine during pregnancy

    Bravo N, Peralta S, Grimalt JO, Martínez MÁ, Rovira J, Schuhmacher M

    Environ Res

    2019 Dec 5;182:109003

    10.1016/j.envres.2019.109003

    Seasonal characterization and dosimetry-assisted risk assessment of indoorparticulate matter (PM(10-25), PM(25-025), and PM(025)) collected indifferent schools

    Sánchez-Soberón F, Rovira J, Sierra J, Mari M, Domingo JL, Schuhmacher M

    Environ Res

    2019 Aug;175:287-296

    10.1016/j.envres.2019.05.035

     

    Physiology-based toxicokinetic modelling in the frame of the European HumanBiomonitoring Initiative

    Sarigiannis DA, Karakitsios S, Dominguez-Romero E, Papadaki K, Brochot C,Kumar V, Schuhmacher M, Sy M, Mielke H, Greiner M, Mengelers M, Scheringer M

    Environ Res

    2019 May;172:216-230

    10.1016/j.envres.2019.01.045

    Review

    Early-life intake of major traceElements, bisphenol A, tetrabromobisphenol A and fatty acids: Comparing human milk andcommercial infant formulas

    Martínez MÁ, Castro I, Rovira J, Ares S, Rodríguez JM, Cunha SC, Casal S,Fernandes JO, Schuhmacher M, Nadal M

    Environ Res

    2019 Feb;169:246-255

    10.1016/j.envres.2018.11.017

    PubMed PMID: 30476748

    HumanHealth risks due to exposure to inorganic andorganic chemicals from textiles: A review

    Rovira J, Domingo JL

    Environ Res

    2019 Jan;168:62-69

    0.1016/j.envres.2018.09.027

    Review

    Human biomonitoring to evaluate exposure to toxic and essential trace elements during pregnancy. Part A. concentrations in maternal blood, urine and cord blood.

    Bocca B, Ruggieri F, Pino A, Rovira J, Calamandrei G, Martínez MÁ, Domingo JL, Alimonti A, Schuhmacher M.

    Environ Res

    10.1016/j.envres.2019.108599

    Selecting mixtures on the basis of dietary exposure and hazarddata: application to pesticide exposure in the European population in relation tosteatosis

    Crépet A, Vanacker M, Sprong C, de Boer W, Blaznik U, Kennedy M,Anagnostopoulos C, Christodoulou DL, Ruprich J, Rehurkova I, Domingo JL, Hamborg Jensen B, Metruccio F, Moretto A, Jacxsens L, Spanoghe P, Senaeve D, van der VoetH, van Klaveren J

    Int J Hyg Environ Health

    2019 Mar;222(2):291-306

    10.1016/j.ijheh.2018.12.002

    PubMed PMID: 30579770

    Biomonitoring of Trace Elements in Hair of Schoolchildren Living Near a HazardousWaste Incinerator-A 20 Years Follow-Up

    Esplugas R, Mari M, Marquès M, Schuhmacher M, Domingo JL, Nadal M

    Toxics

    2019 Oct 1;7(4)

    10.3390/toxics7040052

    Concentrations of nine bisphenol analogues in food purchased fromCatalonia(Spain):Comparison ofCanned and non-canned foodstuffs

    González N, Cunha SC, Ferreira R, Fernandes JO, Marquès M, Nadal M, Domingo JL

    Food Chem Toxicol

    2019 Nov 21:110992

    10.1016/j.fct.2019.110992

    Dietary intake of arsenic, cadmium, mercury and lead by the population ofCatalonia, Spain: Analysis of the temporal trend

    González N, Calderón J, Rúbies A, Timoner I, Castell V, Domingo JL, Nadal M

    Food Chem Toxicol

    2019Oct;132:110721

    10.1016/j.fct.2019.110721

    Oral exposureOf rats to dienestrol during gestation andlactation: EffectsOn the reproductive systemOf maleOffspring

    Schreiber E, Alfageme O, Garcia T, González N, Sirvent JJ, Torrente M, GómezM, Domingo JL

    Food ChemToxicol

    2019 Jun;128:193-201

    10.1016/j.fct.2019.04.013

    PubMed PMID: 30986439

    Human exposure to traceelements and PCDD/Fs around aHazardous waste landfill in Catalonia (Spain)

    Herrero M, Rovira J, Marquès M, Nadal M, Domingo JL

    Sci Total Environ

    2019 Dec 30;710:136313

    10.1016/j.scitotenv.2019.136313

    Monitoring dioxins and furans inplasma of individuals living near a hazardous waste incinerator: Temporal trendafter 20 years

    Nadal M, Mari M, Schuhmacher M, Domingo JL

    Environ Res

    2019 Jun;173:207-211

    10.1016/j.envres.2019.03.051

    PubMed PMID: 30927599

    Risk assessment due to dermalexposure of trace elements and indigo dye in jeans: Migration to artificialsweat

    Herrero M, Rovira J, Nadal M, Domingo JL

    Environ Res

    2019 May;172:310-318

    10.1016/j.envres.2019.02.030

    PubMed PMID: 30825680

    Oxidativestress in testesOf rats exposed to n-butylparaben

    Schreiber E, Garcia T, Sharma RP, Torrente M, Domingo JL, Gómez M

    Food Chem Toxicol

    2019Sep;131:110573

    10.1016/j.fct.2019.110573

    APOE genetic background and sex conferdifferent vulnerabilities to postnatal chlorpyrifos exposure and modulate theresponse to cholinergic drugs

    Guardia-Escote L, Basaure P, Peris-Sampedro F, Biosca-Brull J, Cabré M,Sánchez-Santed F, Domingo JL, Colomina MT

    Behav Brain Res

    2019 Dec 30;376:112195

    10.1016/j.bbr.2019.112195

    OccurrenceOf environmentalpollutants in foodstuffs: A reviewOfOrganic vs conventional food

    González N, Marquès M, Nadal M, Domingo JL

    Food ChemToxicol

    2019 Mar;125:370-375

    10.1016/j.fct.2019.01.021

    Review

    Human exposure totrace elements, aromatic amines and formaldehyde in swimsuits: Assessment of theHealth risks

    Herrero M, Rovira J, Esplugas R, Nadal M, Domingo JL

    Environ Res

    2019 Nov 22:108951

    10.1016/j.envres.2019.108951

    Concentrations of PCDD/Fs in Human Blood: A Review ofData from theCurrent Decade

    Marquès M, Domingo JL

    Int J Environ Res Public Health

    2019 Sep24;16(19)

    10.3390/ijerph16193566

    Exposure tochlorpyrifos at different ages triggers APOE genotype-specific responses insocial behavior, body weight and hypothalamic geneExpression

    Basaure P, Guardia-Escote L, Biosca-Brull J, Blanco J, Cabré M,Peris-Sampedro F, Sánchez-Santed F, Domingo JL, Colomina MT

    Environ Res

    2019 Nov;178:108684

    10.1016/j.envres.2019.108684

    Human exposure to per- and polyfluoroalkyl substances(PFAS) through drinking water: A review of the recent scientific literature

    Domingo JL, Nadal M

    Environ Res

    2019 Oct;177:108648

    10.1016/j.envres.2019.108648

    PubMed PMID: 31421451

    Metals risk assessment for children's health inwater and particulateMatter in a southeastern Brazilian city

    Alves RIS, Machado GP, Zagui GS, Bandeira OA, Santos DV, Nadal M, Sierra J, Domingo JL, Segura-Muñoz SI

    Environ Res

    2019 Oct;177:108623

    10.1016/j.envres.2019.108623

    Human biomonitoring to evaluate exposure to toxic and essential trace elements during pregnancy Part Aconcentrations in maternalblood, urine and cord blood

    Bocca B, Ruggieri F, Pino A, Rovira J, Calamandrei G, Martínez MÁ, DomingoJL, Alimonti A, Schuhmacher M

    Environ Res

    2019 Oct;177:108599

    10.1016/j.envres.2019.108599

    PubMed PMID: 31374401

    Quantification of eight bisphenol analogues in blood and urine samples ofworkers in a hazardous waste incinerator

    González N, Cunha SC, Monteiro C, Fernandes JO, Marquès M, Domingo JL, NadalM

    Environ Res

    2019 Sep;176:108576

    10.1016/j.envres.2019.108576

    Metals in biological tissuesof the population living near a hazardous waste incinerator in Catalonia, Spain: Two decades of follow-up

    Nadal M, García F, Schuhmacher M, Domingo JL

    Environ Res

    2019 Sep;176:108578

    10.1016/j.envres.2019.108578

    Prenatal exposure toPFOSandPFOA in aPregnant women cohort of Catalonia, Spain

    Rovira J, Martínez MÁ, Sharma RP, Espuis T, Nadal M, Kumar V, Costopoulou D,Vassiliadou I, Leondiadis L, Domingo JL, Schuhmacher M

    Environ Res

    2019Aug;175:384-392

    10.1016/j.envres.2019.05.040

    PubMedPMID: 31154228

    Hemodialysis WaterParameters as Predisposing Factors for Anemia in Patients in Dialytic Treatment: Application of Mixed Regression Models

    Suzuki MN, Fregonesi BM, Machado CS, Zagui GS, Kusumota L, Suzuki AK, daCosta JAC, Llopart JS, Nadal M, Domingo JL, Segura-Muñoz S

    Biol Trace Elem Res

    2019Jul;190(1):30-37

    10.1007/s12011-018-1515-7

    Role of Melatonin in Aluminum-RelatedNeurodegenerative Disorders: aReview

    Esparza JL, Gómez M, Domingo JL

    Biol Trace Elem Res

    2019Mar;188(1):60-67

    10.1007/s12011-018-1372-4

    Concentrations of dioxins andfurans in breast milk of women living near a hazardous waste incinerator inCatalonia, Spain

    Schuhmacher M, Mari M, Nadal M, Domingo JL

    Environ Int

    2019 Apr;125:334-341

    10.1016/j.envint.2019.01.074

    PubMed PMID: 30739053

    Soil and indoor dust as environmental media of human exposure to As, Cd, Cu, and Pb near a copper smelter in central Chile

    Berasaluce M., Mondaca P., Schuhmacher M., Bravo M., Sauvé S., Navarro-Villaroel C., Dovetyarova e.a., Neaman A

    J Trace Elem Med Biol

    2019 July; 54:156-162

    10.1016/j.jtemb.2019.04.006

  • Title: Sustainable plant protection transition: A global health approach (SPRINT) H2020-SFS-2018-2020.

    Funding entity: Comission of the European Communities

    Duration: 2020-2025

    Principal Investigator: Martí Nadal Lomas

  • Title: Exposición temprana a sustancias químicas a través de materiales textiles: evaluación de riesgos para la salud. Early-life exposure to chemical substances through textile materials: health risk assessment (PID2019-104443GB-I0).

    Funding entity: Ministerio de ciencia, innovación y universidades

    Duration: 2020-2023

    Principal Investigator: Martí Nadal Lomas

  • Title: Subvencions per a projectes de recerca a la salut mental en l’àmbit de la recerca i la innovació en salut (PERIS – SLT006/17/00246).

    Funding entity: Fundació Privada Institut d’Investigació Biomèdica de Bellvitge

    Duration: 2018-2021

    Principal Investigator: Mònica Bulló Bonet

  • Title: Modulación nutricional los mirnas relacionados con la diabetes tipo 2 y la enfermedad de alzheimer: hacia un enfoque de salud de precisión (PI19/00854).

    Funding entity: Instituto Carlos III

    Duration: 2020-2022

    Principal Investigator: Mònica Bulló Bonet

Team Members

  • Group leader

    • Josep Lluís Domingo
    • Marta Schuhmacher
  • Senior researcher

    • Paloma Vicens
    • Francisco García Sayago
    • Montse Bellés
    • Luis Heredia
    • Montse Mari
    • Jordi Blanco
    • Jaume Folch
    • Martí Nadal Lomas
    • Victòria Linares
    • Maria Teresa Colomina
    • Mercedes Gómez
    • Jordi Sierra Llopart
    • Vikas Kumar
    • Margarita Torrente
  • Postdoctoral researcher

    • Joaquim Rovira
    • Sooyeon Kim
    • Roser Esplugas Borràs
    • Neus González
    • Montse Marquès
    • María Ángeles Martínez
    • Laia Guàrdia
  • Administrative

    • Pilar Prada
  • Technician

    • Noemí Serra Encinas
    • Anabel Díez Pelegrín
  • PhD student

    • Nuria Gayà Caro
    • Deepika
    • Marta Herrero Casado
  • Temporary (Internship)

    • Nora Expósito