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Metabolomics Interdisciplinary Lab (MiL@b)

NUTRICIÓ I METABOLISME
NUTRICIÓ DIABETIS OBESITAT COLESTEROL
http://metabolomicsplatform.com/
OBJECTIUS

• Top-quality research consolidation.
• Education and training for translational metabolòmics.
• Strengthening international funding attraction.
• Research and technology valorisation.

RESPONSABLES

  • Xavier Correig Blanchar

  • Presentació
  • Línies
  • Membres del grup
  • Membres del grup
  • Projectes / Ajudes
  • Media / Xarxes
  • Publicacions
  • Publicacions
  • Contacte
  • Projectes

La PM te accés a equipament analític d’última generació en espectrometria de masses i ressonància magnètica nuclear, que  permeten l’anàlisi a gran escala de mostres biològiques. L’ús d’estadística avançada, quimiometria i algoritmes multivariants permet transformar un elevat conjunt de dades experimentals en  perfils metabòlics i en última instància en informació clínica. Les dades experimentals són processades per l’equip de la plataforma, facilitant la interpretació dels resultats i proporcionant conclusions clíniques sòlides, rellevants i útils pels diferents grups de recerca.

  • Processat de dades metabolòmiques i identificació de metabòlits per LC-MS i GC-MS. Integració de tecnologies òmiques. Etiquetatge d’isòtops estables i fluxòmica per MS i NMR.
  • Imatges d’espectrometria sense marcatge per aplicacions biològiques.
  • Processat i anàlisi avançat de dades metabolòmiques per a tècniques analítiques i aplicacions clíniques multidimensionals.
  • Metabolòmica per RMN.
  • Metabolòmica toxicològica i ambiental.

  • Títol: AYUDAS JUAN DE LA CIERVA – INCORPORACION 2015
    Referència: IJCI-2015-23158
    Entitat finançadora: Instituto de Salud Carlos III
    Durada: 01/09/2017 – 31/08/2019

  • Títol: TYPE OF ACTION: RELIABLE AND SPECIFIC URINARY BIOMARKERS FOR COLORECTAL CANCER (COLOVOC)
    Referència: H2020-MSCA-IF-2017; PROPOSAL NUMBER: 798038
    Entitat finançadora: MARIE CURIE HORIZON 2020
    Durada: 01/09/2017 – 30/06/2022

  • Títol: ESTANCIAS DE MOVILIDAD EN EL EXTRANJERO ‘JOSE CASTILLEJO’ PARA JOVENES DOCTORES
    Referència: —
    Entitat finançadora: Ministerio de Ciencia, Innovacion y Universidades
    Durada: 08/07/2019 – 30/09/2019

  • Títol:
    Referència: EIN2019-102898
    Entitat finançadora: Ministerio de Ciencia, Innovacion y Universidades
    Durada: 01/06/2019 – 31/05/2020

  • Títol: EPIGENETIC AND METABOLIC ALTERATIONS ASSOCIATED TO EARLY CHILDHOOD EXPOSURE TO AIR POLLUTION AND ITS ROLE IN LATER LIFE CHRONIC DISEASE (ECHOES)
    Referència:
    Entitat finançadora: RECERCA SOCIAL “LA CAIXA”
    Durada: 01/01/2020 – 31/12/2021

  • Títol: Development of a signal and data processing workflow for 2D
    hyphenated chromatography based on multi-way algorithms: Application to urine metabolomics data for colorectal cancer screening (TensorChrom)
    Referència:
    Entitat finançadora: Ministerio de Ciencia, Innovacion y Universidades
    Durada: 01/01/2019 – 31/12/2022

  • Títol: Desarrollo de nuevas tecnologías de histología molecular basadas en espectroscopia de imágenes y su aplicación al estudio del cáncer y la diabetes (hisMOL4CANdia)
    Referència:
    Entitat finançadora: Ministerio de Ciencia, Innovacion y Universidades
    Durada: 01/01/2019 – 31/12/2022

  • Títol Ayudas Juan de la Cierva-incorporación
    Referència: IJCI-2017-33438
    Entitat finançadora: Ministerio de Economía y Competitividad
    Durada: 01/01/2019 – 31/12/2021

  • Title: CB07/08/0014 CIBER

    Funding entity: Instituto de Salud Carlos III

    Duration: 2008 – 2025

    Principal Investigator: Xavier Correig Blanchar

  • CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM). (CB07/08/0014)

  • RED ESPAÑOLA DE METABOLÓMICA

    Año

    Lipid Profiling Using (1)H NMRSpectroscopy

    Gil M, Samino S, Barrilero R, Correig X
    Methods Mol Biol
    2019;2037:35-47
    10.1007/978-1-4939-9690-2_3

    Gelsolin: a new biomarker of disease activity in SLE patients associated with HDL-c

    Parra S, Heras M, Herrero P, Amigó N, Garcés E, Girona J, Correig X, CanelaN, Castro A
    Rheumatology (Oxford)
    10.1093/rheumatology/kez293

    Plasma glucose, triglycerides, VLDL,leptin and resistin levels asPotential biomarkers for myocardial fat in mice

    Rodríguez-Calvo R, Samino S, Guaita-Esteruelas S, Martínez-Micaelo N, HerasM, Girona J, Yanes O, Correig X, Masana L
    Clin Investig Arterioscler
    10.1016/j.arteri.2019.05.001

    Gold Nanoparticle-Assisted Black Silicon Substrates for Mass Spectrometry Imaging Applications

    Iakab SA, Ràfols P, Tajes M, Correig-Blanchar X, García-Altares M.
    ACS Nano. 2020 Jun 23;14(6):6785-6794.
    DOI: 10.1021/acsnano.0c00201

     

    Activation of glycogenolysis and glycolysis in breast cancer stem cell models

    Abad E, Samino S, Yanes O, Potesil D, Zdrahal Z, Lyakhovich A.
    Biochim Biophys Acta Mol Basis Dis. 2020 Oct 1;1866(10):165886.
    DOI: 10.1016/j.bbadis.2020.165886

     

    rMSIproc: an R package for mass spectrometry imaging data processing

    Ràfols P, Heijs B, Del Castillo E, Yanes O, McDonnell LA, Brezmes J, Pérez-Taboada I, Vallejo M, García-Altares M, Correig X.
    Bioinformatics. 2020 Jun 1;36(11):3618-3619.
    DOI: 10.1093/bioinformatics/btaa142

     

    Raman2imzML converts Raman imaging data into the standard mass spectrometry imaging format

    Iakab SA, Sementé L, García-Altares M, Correig X, Ràfols P.
    BMC Bioinformatics. 2020 Oct 9;21(1):448.
    DOI: 10.1186/s12859-020-03789-8

    Endogenous retroelement activation by epigenetic therapy reverses the Warburg effect and elicits mitochondrial-mediated cancer cell death

    Fresquet V, Garcia-Barchino MJ, Larrayoz MJ, Celay J, Vicente C, Fernandez-Galilea M, Larrayoz MJ, Calasanz MJ, Panizo C, Junza A, Han J, Prior C, Fortes P, Pio R, Oyarzabal J, Martínez-Baztán A, Paiva B, Moreno-Aliaga MJ, Odero MD, Agirre X, Yanes O, Prósper F, Martinez-Climent JA
    2020 Dec 19 [Epub ahead of print]. Cancer Discovery.
    DOI: 10.1158/2159-8290.CD-20-1065

     

    Post-translational regulation of retinal IMPDH1 in vivo to adjust GTP synthesis to illumination conditions

    Plana-Bonamaisó A, López-Begines S, Fernández-Justel D, Junza A, Soler-Tapia A, Andilla J, Loza-Alvarez P, Rosa JL, Miralles E, Casals I, Yanes O, de la Villa P, Buey RM, Méndez A.
    Elife. 2020 Apr 7;9:e56418.
    DOI: 10.7554/eLife.56418

    Nucleotide depletion reveals the impaired ribosome biogenesis checkpoint as a barrier against DNA damage

    Pelletier J, Riaño-Canalias F, Almacellas E, Mauvezin C, Samino S, Feu S, Menoyo S, Domostegui A, Garcia-Cajide M, Salazar R, Cortés C, Marcos R, Tauler A, Yanes O, Agell N, Kozma SC, Gentilella A, Thomas G.
    EMBO J. 2020 Jul 1;39(13):e103838.
    DOI: 10.15252/embj.2019103838

    Chemical changes in thirdhand smoke associated with remediation using an ozone generator.

    Tang X, Ramírez Gonzalez N, Russell ML, Maddalena RL, Gundel LA, Destaillats H
    2020 Nov 18 [Epub ahead of print]. Environmental Research.
    DOI: 10.1016/j.envres.2020.110462

    Bariatric surgery decreases oxidative stress and protein glycosylation in patients with morbid obesity

    Carmona-Maurici J, Amigó N, Cuello E, Bermúdez M, Baena-Fustegueras JA, Peinado-Onsurbe J, Pardina E.
    Eur J Clin Invest. 2020 Nov;50(11):e13320.
    DOI: 10.1111/eci.13320

    Habitual Fish Consumption, n-3 Fatty Acids, and Nuclear Magnetic Resonance Lipoprotein Subfractions in Women

    Amigó N, Akinkuolie AO, Chiuve SE, Correig X, Cook NR, Mora S.
    J Am Heart Assoc. 2020 Mar 3;9(5):e014963.
    DOI: 10.1161/JAHA.119.014963

     

    rMSIcleanup: an open-source tool for matrix-related peak annotation in mass spectrometry imaging and its application to silver-assisted laser desorption/ionization

    Baquer G, Sementé L, García-Altares M, Lee YJ, Chaurand P, Correig X, Ràfols P.
    J Cheminform. 2020 Jul 22;12(1):45.
    DOI: 10.1186/s13321-020-00449-0

    Glycoprotein Profile Assessed by (1)H-NMR as a Global Inflammation Marker in Patients with HIV Infection. A Prospective Study

    Malo AI, Rull A, Girona J, Domingo P, Fuertes-Martín R, Amigó N, Rodríguez-Borjabad C, Martínez-Micaelo N, Leal M, Peraire J, Correig X, Vidal F, Masana L.
    J Clin Med. 2020 May 4;9(5):1344.
    DOI: 10.3390/jcm9051344

    Plasma Metabolomic Profiling Associates Bicuspid Aortic Valve Disease and Ascending Aortic Dilation with a Decrease in Antioxidant Capacity

    Martínez-Micaelo N, Ligero C, Antequera-González B, Junza A, Yanes O, Alegret JM.
    J Clin Med. 2020 Jul 13;9(7):2215.
    DOI: 10.3390/jcm9072215

     

    GlycA Levels during the Earliest Stages of Rheumatoid Arthritis: Potential Use as a Biomarker of Subclinical Cardiovascular Disease

    Rodríguez-Carrio J, Alperi-López M, López P, Pérez-Álvarez ÁI, Gil-Serret M, Amigó N, Ulloa C, Benavente L, Ballina-García FJ, Suárez A.
    J Clin Med. 2020 Aug 1;9(8):2472.
    DOI: 10.3390/jcm9082472

    Environmental arginine controls multinuclear giant cell metabolism and formation

    Brunner JS, Vulliard L, Hofmann M, Kieler M, Lercher A, Vogel A, Russier M, Brüggenthies JB, Kerndl M, Saferding V, Niederreiter B, Junza A, Frauenstein A, Scholtysek C, Mikami Y, Klavins K, Krönke G, Bergthaler A, O’Shea JJ, Weichhart T, Meissner F, Smolen JS, Cheng P, Yanes O, Menche J, Murray PJ, Sharif O, Blüml S, Schabbauer G.
    Nat Commun. 2020 Jan 22;11(1):431.
    DOI: 10.1038/s41467-020-14285-1

     

    Exhaled volatile organic compounds analysis in clinical pediatrics: a systematic review

    Sola Martínez RA, Pastor Hernández JM, Yanes Torrado Ó, Cánovas Díaz M, de Diego Puente T, Vinaixa Crevillent M.
    2020 Sep 12 [Epub ahead of print]. Pediatr Res.
    DOI: 10.1038/s41390-020-01116-8

     

     

    Fatty acid bindingprotein 4 (FABP4) as a potential biomarker reflecting myocardial lipid storage intype 2 diabetes

    Rodríguez-Calvo R, Girona J, Rodríguez M, Samino S, Barroso E, deGonzalo-Calvo D, Guaita-Esteruelas S, Heras M, van der Meer RW, Lamb HJ, Yanes O,Correig X, Llorente-Cortés V, Vázquez-Carrera M, Masana L
    Metabolism
    10.1016/j.metabol.2019.04.007

    Epigenetic loss of theEndoplasmicreticulum-associated degradation inhibitor SVIP induces cancer cell metabolicreprogramming

    Llinàs-Arias P, Rosselló-Tortella M, López-Serra P, Pérez-Salvia M, SetiénF, Marin S, Muñoz JP, Junza A, Capellades J, Calleja-Cervantes ME, Ferreira HJ,de Moura MC, Srbic M, Martínez-Cardús A, de la Torre C, Villanueva A, Cascante M,Yanes O, Zorzano A, Moutinho C, Esteller M
    JCI Insight
    10.1172/jci.insight.125888

    Essentiality of fatty acid synthase in the 2D to anchorage-independent growth transition in transforming cells

    Bueno M.J., Jimenez-Renard V., Samino S., Capellades J., Junza A., Lopez-Rodriguez M.L., Garcia-Carceles J., Lopez-Fabuel I., Bolanos J.P., Chandel N.S., Yanes O., Colomer R., Quintela-Fandino M.
    Nat Commun
    10.1038/s41467-019-13028-1

    Lipid ProfileRather Than theLCAT Mutation Explains Renal Disease in FamilialLCAT Deficiency

    Lamiquiz-Moneo I, Civeira F, Gómez-Coronado D, Blanco-Vaca F,Villafuerte-Ledesma HM, Gil M, Amigó N, Mateo-Gallego R, Cenarro A
    J Clin Med
    10.3390/jcm8111860

    Adaptation to HIF1α Deletion in Hypoxic Cancer Cells by Upregulation of GLUT14 and Creatine Metabolism

    Llauradó G, Amigó N, Cano A, Ballesta S, Albert L, Mazarico I,Fernández-Veledo S, Pedro-Botet J, Vendrell J, González-Clemente JM
    Mol Cancer Res
    10.1158/1541-7786.MCR-18-0315

    Changes in Plasma MetaboliteConcentrations after a Low-Glycemic IndexDiet Intervention

    Hernández-Alonso P, Giardina S, Cañueto D, Salas-Salvadó J, Cañellas N,Bulló M
    Mol Nutr Food Res
    10.1002/mnfr.201700975

    CliqueMS: aComputational tool for annotating in-sourcemetabolite ions from LC-MS untargeted metabolomics data based on aCoelutionsimilarity network

    Senan O, Aguilar-Mogas A, Navarro M, Capellades J, Noon L, Burks D, Yanes O,Guimerà R, Sales-Pardo M
    Bioinformatics
    10.1093/bioinformatics/btz207

    Serum Paraoxonase-1-Related Variables andLipoprotein Profile in Patients with Lung or Head and Neck Cancer: Effect ofRadiotherapy

    Rodríguez-Tomàs E, Murcia M, Arenas M, Arguís M, Gil M, Amigó N, Correig X,Torres L, Sabater S, Baiges-Gayà G, Cabré N, Luciano-Mateo F, Hernández-Aguilera A, Fort-Gallifa I, Camps J, Joven J
    Antioxidants (Basel)
    10.3390/antiox8070213

    Adaptation to HIF1α Deletion in Hypoxic Cancer Cells by Upregulation of GLUT14and Creatine Metabolism

    Valli A, Morotti M, Zois CE, Albers PK, Soga T, Feldinger K, Fischer R,Frejno M, McIntyre A, Bridges E, Haider S, Buffa FM, Baban D, Rodriguez M, Yanes O, Whittington HJ, Lake HA, Zervou S, Lygate CA, Kessler BM, Harris AL
    Mol Cancer Res
    10.1158/1541-7786.MCR-18-0315

    HDL Triglycerides: A New Marker of Metabolicand Cardiovascular Risk

    Girona J, Amigó N, Ibarretxe D, Plana N, Rodríguez-Borjabad C, Heras M,Ferré R, Gil M, Correig X, Masana L
    Int J Mol Sci
    10.3390/ijms20133151

    Biological Response to Meal Ingestion: Gender Differences

    Monrroy H, Borghi G, Pribic T, Galan C, Nieto A, Amigo N, Accarino A,Correig X, Azpiroz F
    Nutrients
    10.3390/nu11030702

    Meal Enjoyment and Tolerance in Women andMen

    Monrroy H, Pribic T, Galan C, Nieto A, Amigo N, Accarino A, Correig X,Azpiroz F
    Nutrients
    10.3390/nu11010119

    CD98hc (SLC3A2) sustains amino acid and nucleotide availability forcell Cycle progression

    CD98hc (SLC3A2) sustains amino acid and nucleotide availability forcell Cycle progression
    Sci Rep
    10.1038/s41598-019-50547-9

    Glycoprotein A and B Height-to-WidthRatios as Obesity-Independent Novel Biomarkers of Low-Grade Chronic Inflammation in Women with Polycystic Ovary Syndrome (PCOS)

    Fuertes-Martín R, Moncayo S, Insenser M, Martínez-García MÁ, Luque-Ramírez M,Grau NA, Blanchar XC, Escobar-Morreale HF
    J Proteome Res
    10.1021/acs.jproteome.9b00528

    Epigenetic Regulation at the Interplay Between GutMicrobiota and Host Metabolism

    Miro-Blanch J, Yanes O
    Front Genet
    10.3389/fgene.2019.00638

    RMSIKeyIon: An Ion FilteringR Package for UntargetedAnalysis of Metabolomic LDI-MS Images

    Del Castillo E, Sementé L, Torres S, Ràfols P, Ramírez N, Martins-Green M,Santafe M, Correig X
    Metabolites
    10.3390/metabo9080162

    Dysfunctional LAT2 Amino Acid Transporter Is AssociatedWith Cataract in Mouse and Humans

    Knöpfel EB, Vilches C, Camargo SMR, Errasti-Murugarren E, Stäubli A, Mayayo C, Munier FL, Miroshnikova N, Poncet N, Junza A, Bhattacharya SS, Prat E, BerryV, Berger W, Heon E, Moore AT, Yanes Ó, Nunes V, Palacín M, Verrey F,Kloeckener-Gruissem B
    Front Physiol
    10.3389/fphys.2019.00688

    Low-densityLipoprotein net charge is a risk factor foratherosclerosis inLupus patients independent ofLipid concentrations

    Rodríguez M, Guardiola M, Oliva I, Carles Vallvé J, Ferré R, Masana L, ParraS, Ribalta J, Castro A
    Int J Rheum Dis
    10.1111/1756-185X.13445

    Silicon-Based Laser Desorption Ionization Mass Spectrometry for the Analysis of Biomolecules: A Progress Report

    Iakab S.A., Rafols P., Garcia-Altares M., Yanes O., Correig X.
    Advance Functional Material
    https://doi.org/10.1002/adfm.201903609

    Año

    SUCNR1 coordinates metabolic flux, mitochondrial function, and nutrient-dependent adaptation in hepatocytes.

    Marsal-Beltran A, Salmerón-Pelado L, Ribas-Latre A, Repollés-de-Dalmau M, Rodríguez-Peña MM, Núñez-Roa C, Badia J, Madeira A, Novoa E, Beltrà M, Plata-Gómez AB, Capellades J, Escolà-Gil JC, Zorzano A, Yanes Ó, Efeyan A, Nogueiras R, Gracia-Sancho J, Vendrell J, Ceperuelo-Mallafré V, Fernández-Veledo S. 12/06/2026. Science advances. 12. PMID: 42284407. doi: 10.1126/sciadv.aec8873

    Role of activity and fibrosis in the MASLD atherogenic momentum through advanced lipidomics.

    Blanco-Echevarría A, Costa Segovia R, Guijarro Herraiz C, García Izquierdo B, Guadalix S, Pérez Carreras M, Rodríguez Gil Y, de Castro Martínez M, Amigó N, D’Avola D, Lumbreras Bermejo C, Martínez-Urbistondo D. 13/05/2026. Plos One. 21. PMID: 42127133. doi: 10.1371/journal.pone.0343134

    Limitations of current animal models in atherosclerosis: an integrative multiomics perspective.

    Kardassis D, Amigó N, Mitic T. 22/04/2026. European Heart Journal. 47. PMID: 41556948. doi: 10.1093/eurheartj/ehaf997

    Chronic kidney disease induces a distinct lipidomic signature and accelerates atherosclerosis progression in a novel minipig model.

    Bermúdez-López M, Nogales P, Martí-Antonio M, Castro-Boqué E, de Lamo VM, Beà-Menchón L, Luis-Lima S, Porrini E, Sanchez-Salguero X, Jové M, Obis E, Mota-Martorell N, Pérez-Gómez A, Garcia-Carrasco A, Bozic M, Guajardo J, Pérez-Sánchez CJ, Cambray S, Amigó N, Pamplona R, Bentzon JF, Valdivielso JM. 02/04/2026. Laboratory Animal Research. 42. PMID: 41928358. doi: 10.1186/s42826-026-00274-w

    Multiomics for Risk Stratification in Atherosclerotic Cardiovascular Disease.

    Nordestgaard LT, Magni P, Sopic M, Chemaly M, Matic L, Dalila N, Trindade F, Wolford BN, Rodriguez-Hernandez Z, Amigó N, Catapano AL, Masana L, Devaux Y. 01/04/2026. Circulation-Genomic and Precision Medicine. 19. PMID: 41878824. doi: 10.1161/CIRCGEN.125.005451

    Effect of combined aerobic and resistance training on kidney health in adults with type 2 diabetes: A randomized controlled trial.

    Burton O, Díaz-López A, Villalobos F, Pedret R, Arija V. 24/03/2026. DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS. 20. PMID: 41886945. doi: 10.1016/j.dsx.2026.103404

    Assessment of physical status and analysis of lipidomic and metabolomic alterations in patients with Post-COVID-19 condition.

    Pavón R, Parra S, Rubio FJ, Feliu M, Ríos M, Iftimie S, Rovira C, Amigó N, Cabau L, Martínez-Micaelo N, Castro A. 03/03/2026. Plos One. 21. PMID: 41774679. doi: 10.1371/journal.pone.0341192

    Antifungal and anti-virulence activities of cinnamon, thyme, and clove essential oils against Candida species.

    Ahaik I, Nunez-Rodriguez JC, Abelló-Cros S, Yanes O, Bouhdid S, Gabaldón T. 02/03/2026. Frontiers in Pharmacology. 17. PMID: 41847137. doi: 10.3389/fphar.2026.1756267

    Disease-specific crosstalk of Alistipes with lipoprotein profiles in overweight individuals at high cardiometabolic risk.

    Cuevas-Sierra A, Higuera-Gómez A, de Cuevillas B, Amigó N, Martínez-Urbistondo M, Castejón R, Vargas JA, Martínez JA. 13/02/2026. Scientific Reports. 16. PMID: 41688554. doi: 10.1038/s41598-026-36024-0

    FASN targeting by G28UCM impairs mitochondrial fatty acid synthesis and reveals a FASN-SDHB synthetic interaction.

    Wilfinger-Lutz N, Kuehrer KM, Bueno MJ, Schwaiger-Haber M, Ann WW, Krejci K, Mekis R, Gobbo Oliveira Erünlü N, Miller A, Junza A, Reipert S, Bergmann M, Yanes O, Haschemi A, Koellensperger G, Quintela-Fandino M, Nowikovsky K. 01/02/2026. Pharmacological Research. 224. PMID: 41520938. doi: 10.1016/j.phrs.2026.108087

    Multilayer metabolomic integration reveals bioenergetic disruption in Long COVID.

    García-Hidalgo MC, Mota-Martorell N, González J, Benítez ID, Company-Marín I, Jové M, Barbé F, Amigó N, Pamplona R, de Gonzalo-Calvo D, Torres G. 20/01/2026. Journal Of Translational Medicine. 24. PMID: 41559790. doi: 10.1186/s12967-026-07684-3

    Small intestine is not colon: a new in vitro model of the human ileum microbiome integrating the mucosal microenvironment and feeding status.

    Bron A, Beltramo C, Durif C, Arora T, Deschamps C, Couturier I, Domingo-Almenara X, Otero YF, Denis S, Van de Wiele T, Blanquet-Diot S. 31/12/2025. Gut microbes. 17. PMID: 41277251. doi: 10.1080/19490976.2025.2579353

    Comparing Campylobacter jejuni to three other enteric pathogens in OligoMM12 mice reveals pathogen-specific host and microbiota responses

    Herzog, MKM, Peters, A, Shayya, N, Cazzaniga, M, Bra, KK, Arora, T, Barthel, M, Gül, E, Maurer, L, Kiefer, P, Christen, P, Endhardt, K, Vorholt, JA, Frankel, G, Heimesaat, MM, Bereswill, S, Gahan, CGM, Claesson, MJ, Domingo-Almenara, X, Hardt, WD. 31/12/2025. Gut microbes. 17. PMID: 39835346. doi: 10.1080/19490976.2024.2447832

    A Perspective on Unintentional Fragments and Their Impact on the Dark Metabolome, Untargeted Profiling, Molecular Networking, Public Data, and Repository Scale Analysis

    El Abiead, Y, Mohanty, I, Xing, SP, Rutz, A, Charron-Lamoureux, V, Damiani, T, Lu, WY, Patti, GJ, Zamboni, N, Yanes, O, Dorrestein, PC. 22/12/2025. JACS Au. 5. PMID: 41450660. doi: 10.1021/jacsau.5c01063

    A Robust Multivariate Approach Unveils a 1H-NMR-Based Spectral Metabolomics Signature Predictive of Cardiovascular Disease in People with Type 2 Diabetes: A Prospective Di@bet.es Cohort Study

    Rehues, P, Guardiola, M, Amigo, N, Rojo-Martinez, G, Mallol-Parera, R, Ribalta, J. 05/12/2025. Journal Of Proteome Research. 24. PMID: 41258650. doi: 10.1021/acs.jproteome.5c00662

    Guanine and pregnenolone sulfate are associated with incident type 2 diabetes in two independent populations

    Barranco-Altirriba, M, Granado-Casas, M, Yanes, O, Capellades, J, Junza, A, Franch-Nadal, J, Vendrell, J, Llaurado, G, Valdés, S, García-Escobar, E, Bermúdez-Lopez, M, Valdivielso, JM, Lopez-Lifante, VM, Herrero-Alonso, C, Falguera, M, Vilanova, MB, Arteaga, I, Torán-Monserrat, P, Perera-Lluna, A, Castelblanco, E, Mauricio, D. 03/12/2025. Frontiers in endocrinology. 16. PMID: 41416067. doi: 10.3389/fendo.2025.1706886

    Widespread lipoprotein alterations in a REDUCE-IT like population: The icosapent ethyl (IPE)-NMR avatar study

    Masana, L, Torné, P, Garcia-Moll, X, Dalli, E, Amigo, N. 01/11/2025. Nutrition Metabolism And Cardiovascular Diseases. 35. PMID: 40651885. doi: 10.1016/j.numecd.2025.104199

    A Potential Ratio for Detecting Subclinical Atherosclerosis: Insight into Advanced NMR Lipid Profiles in Severe Obesity

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    HUMORAL RESPONSES AGAINST HDL ARE LINKED TO LIPOPROTEIN TRAITS, ATHEROSCLEROSIS, INFLAMMATION AND PROTEOMIC PATHOGENIC PATHWAYS DURING EARLY ARTHRITIS STAGES

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    Urinary Metabolomics Study on the Protective Role of Cocoa in Zucker Diabetic Rats via 1H-NMR-Based Approach

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  • Title: Foment de la detecció precoç del càncer colorectal (crcimpact)

    Funding entity: AGENCIA DE GESTIO D’AJUTS UNIVERSITARIS I DE RECERCA

    Duration: 2026-2028

    Principal Investigator: CUMERAS OLMEDA, RAQUEL

    Investigators: FORTUNY PARULL, LAIA; GALCERAN PADRÓS, JAUME JOSEP MARIA; LÓPEZ RUBIO, ROCÍO; MIRACLE HUGUET, CRISTINA; MIRACLE HUGUET, CRISTINA; RODRÍGUEZ BALADA, MARTA

  • Title: Rapid urine-based lateral flow assay for early detection of colorectal cancer metastasis (metaspread test). convocatoria dels ajuts d’industria del coneixement (idc) per a l’any 2024, modalitat b. producte

    Funding entity: AGENCIA DE GESTIO D’AJUTS UNIVERSITARIS I DE RECERCA

    Duration: 2026

    Principal Investigator: CUMERAS OLMEDA, RAQUEL

    Investigators: , GUILERA MORILLA, MJ; ANDREU INGLES, MARC; CERVELLO ARAN, PILAR; CERVELLO ARAN, PILAR; LLAMBRICH RODRIGUEZ, MARIA; MARGALEF I BURGOS, ANNABEL; ONOIU, ALINA IULIANA

  • Title: Cd25/00016_contratos sara borrell_mahsa naghavi sheikholeslami

    Funding entity: INSTITUTO CARLOS III

    Duration: 2026-2030

    Principal Investigator: RAMÍREZ GONZÁLEZ, NOELIA

    Investigators: NAGHAVI SHEIKHOLESLAMI, MAHSA

  • Title: Multi-omics biomarker discovery and validation for colorectal cancer: a pathway to precision oncology

    Funding entity: INSTITUTO CARLOS III

    Duration: 2026-2031

    Principal Investigator: CUMERAS OLMEDA, RAQUEL

    Investigators: CERVELLO ARAN, PILAR

  • Title: Cp25/00036 – contratos miguel servet_raquel cumeras olmeda.

    Funding entity: INSTITUTO CARLOS III

    Duration: 2026-2032

    Principal Investigator: CUMERAS OLMEDA, RAQUEL

  • Title: Tb-omics: innovative tuberculosis screening and diagnostic tool system based on specific biomarkers in urine

    Funding entity: AGENCIA ESTATAL DE INVESTIGACION

    Duration: 2025-2030

    Principal Investigator: VINAIXA CREVILLENT, MARIA

    Investigators: SAMINO GENÉ, SARA

  • Title: 2025 step 00396_ajuts per a la contractació de personal de investigador predoctoral en formació en els àmbits de les tecnologies step ( fi-step)_sarai cuesta mañas

    Funding entity: AGENCIA DE GESTIO D’AJUTS UNIVERSITARIS I DE RECERCA

    Duration: 2025-2030

    Principal Investigator: RAMÍREZ GONZÁLEZ, NOELIA

    Investigators: CUESTA MAÑAS, SARAI

  • Title: Caracterización de la exposición individual a contaminación atmosférica en pacientes pediátricos con asma (asthma)

    Funding entity: SOCIEDAD ESPAÑOLA DE NEUMOLOGIA PEDIATRICA

    Duration: 2025-2029

    Principal Investigator: RAMÍREZ GONZÁLEZ, NOELIA

  • Title: Nuevos metodos de analiticos y de biomonitorizacion para caracterizar el exposoma quimico prenatal

    Funding entity: AGENCIA ESTATAL DE INVESTIGACION

    Duration: 2025-2029

    Principal Investigator: RAMÍREZ GONZÁLEZ, NOELIA

    Investigators: , BARRI , AMINA; , GUERRINI , CAMILLA; BARRI BARRI, AMINA

  • Title: Integration of metabolomics and genomics for the early diagnosis of colorectal cancer: desing of a prediction tool (imagine)

    Funding entity: INSTITUTO CARLOS III

    Duration: 2025-2029

    Principal Investigator: CUMERAS OLMEDA, RAQUEL

    Investigators: BADIA CABRE, JOAN; BALLESTE PERIS, BELEN; CABEZAS MONTERO, INÉS MARÍA; FERNANDEZ CASTILLEJO, SARA; MARTINEZ CEREZO, FRANCISCO JOSE; MIRACLE HUGUET, CRISTINA; PEÑA GONZÁLEZ,KARLA BEATRIZ; RODRÍGUEZ BALADA, MARTA; ROIG BOURGINE, BARBARA; SANS MATEU, Mª TERESA; SÁNCHEZ MARÍN, ANTONIO; VILLALBA ORDOÑEZ, HECTOR

  • Title: Life fluids: descobrint com el que mengem transforma els nostres biofluids

    Funding entity: FUNDACIO CATALANA PER A LA RECERCA

    Duration: 2025-2027

    Principal Investigator: CUMERAS OLMEDA, RAQUEL

    Investigators: , MARGALEF I BURGOS, ANNABEL

  • Title: Doctorats industrials 2023-identificacio de biomarcadors de cancer de pell mitjançant la combinacio de metabolomica, lipid

    Funding entity: AGENCIA DE GESTIO D’AJUTS UNIVERSITARIS I DE RECERCA

    Duration: 2024-2029

    Principal Investigator: CUMERAS OLMEDA, RAQUEL

    Investigators: , BADIA CABRE, JOAN; , CERVELLO ARAN, PILAR; , GABALDON COLOMINA, YERAY; , LLAMBRICH RODRIGUEZ, MARIA; , MARGALEF I BURGOS, ANNABEL; , VILLALBA ORDOÑEZ, HECTOR

  • Title: Fi23/00032 contratos predoctorales de formacion en investigacion en salud. camilla guerrini- noelia ramirez gonzalez

    Funding entity: INSTITUTO CARLOS III

    Duration: 2024-2029

    Principal Investigator: RAMÍREZ GONZÁLEZ, NOELIA

    Investigators: GUERRINI , CAMILLA

  • Title: 2021 prod 00112. ajuts d’industria del coneixement per a l’any 2021. modalitat b. ajuts producte title: an e-infrastructure based on cloud and edge computing for data analysis in metabolomics acronym: datoma

    Funding entity: AGENCIA DE GESTIO D’AJUTS UNIVERSITARIS I DE RECERCA

    Duration: 2023-2025

    Principal Investigator: YANES TORRADO, ÓSCAR

    Investigators: , BENABDELKRIM ZAKAN, USAMA; BEL RIBES, EDUARD; CAPELLADES TOMAS, JORDI; DOMINGO ALMENARA, XAVIER; GARCÍA LÓPEZ, PEDRO ANTONIO; GINE BERTOMEU, ROGER; GINE BERTOMEU, ROGER; RÀFOLS SOLER, PERE; VINAIXA CREVILLENT, MARIA

  • Title: Programa de fons de patents ginjol corresponent a la 11ª edicio (any 2022). conveni: 2022-11-009

    Funding entity: FUNDACIO INSTITUCIO DELS CENTRES DE RECERCA DE CATALUNYA

    Duration: 2023-2025

    Principal Investigator: RAMÍREZ GONZÁLEZ, NOELIA

  • Title: Cpp2022-010039 proyectos en colaboracion publico privada 2022 harmoni

    Funding entity: AGENCIA ESTATAL DE INVESTIGACION

    Duration: 2023-2028

    Principal Investigator: VINAIXA CREVILLENT, MARIA

    Investigators: AMIGÓ GRAU, NÚRIA; BEL RIBES, EDUARD JOSEP; BURTON , OLIVIA LUCY

  • Title: Exposome: identificando el metaboloma de la obesidad infantil y la correlacion con el exposoma personal.

    Funding entity: INSTITUTO CARLOS III

    Duration: 2023-2028

    Principal Investigator: RAMÍREZ GONZÁLEZ, NOELIA

    Investigators: ESCRIBANO SUBIAS, JUAQUIN; FELIU ROVIRA, ALBERT; FERRE PALLAS, NATALIA; GUERRINI , CAMILLA; LUQUE MORENO, VERÒNICA

  • Title: Proyectos de i+d+i vinculados a la medicina personalizada y terapias avanzadas:

    Funding entity: INSTITUTO CARLOS III

    Duration: 2023-2027

    Principal Investigator: RAMÍREZ GONZÁLEZ, NOELIA

    Investigators: , GUERRINI , CAMILLA; , RODA PITARG, DÍDAC; BLANCH MARTÍNEZ, XAVIER; BORRULL BALLARÍN, FRANCESC; ESCRIBANO SUBIAS, JOAQUIN; FERNANDEZ MUÑOZ, ESTEVE; FERRE PALLAS, NATALIA; LLOBET VALERO, EDUARD; LUQUE MORENO, VERONICA; MARCÉ RECASENS, ROSA MARIA; NAGHAVI SHEIKHOLESLAMI, MAHSA; PUSCASU , ALBERTO CONSTANTINO; RÚA HERNÁNDEZ, ELIZABETH JOHANNA; VALLECILLOS MARSAL, LAURA

  • Title: 2021 llav 00050. ajuts d’industria del coneixement per a l’any 2021. modalitat a. ajuts llavor ionomica urinaria en la progressio del cancer colorectal

    Funding entity: AGENCIA DE GESTIO D’AJUTS UNIVERSITARIS I DE RECERCA

    Duration: 2022-2023

    Principal Investigator: CUMERAS OLMEDA, RAQUEL

    Investigators: LLAMBRICH RODRIGUEZ, MARIA

  • Title: Marato tv3: 240/c/2020 towards improving clinical management and care of lymphangioleiomyomatosis: integrative study of biomarkers and therapies (improve) coordinador: miguel angel pujana –institut de recerca biomedica bellvitge. subprojecte iispv marato de tv3

    Funding entity: FUNDACIO LA MARATO TV3

    Duration: 2022-2025

    Principal Investigator: YANES TORRADO, ÓSCAR

  • Title: Pandemies 2020 convocatoria: ‘replegar-se per creixer: l’impacte de les pandemies en un mon sense fronteres visibles’ pandemies 2020 – ref. 2020 pande 00082 visioning

    Funding entity: AGENCIA DE GESTIO D’AJUTS UNIVERSITARIS I DE RECERCA

    Duration: 2022-2023

    Principal Investigator: CORREIG BLANCHAR, XAVIER

    Investigators: AMIGO GRAU, NURIA; BADIA APARICIO, JOSEP MARIA; BREZMES LLECHA, JESÚS JORGE; BULLO BONET, MONICA; CABAU PARRA, LYDIA; GIRONA TELL, JOSEFA; IBARRECHE GUEREDIAGA, DAIANA; MARTINEZ MICAELO, NIEVES BEATRIZ; MASANA MARÍN, LUIS; MERINO RUIZ, CARLA MELISSA; PAPANDREOU ., CHRISTOFOROS; PLANA GIL, NÚRIA; REHUES MASIP, PERE; SOLER BORONAT, ORIA; VINAIXA CREVILLENT, MARIA; YANES TORRADO, OSCAR; ZINCU, CRISTINA

  • Title: Convocatoria d’ajuts per al foment de la cultura cientifica a catalunya en la seva primera edicio 2021: life fluids: quins fluids tenim al cos huma?

    Funding entity: FUNDACIO CATALANA PER A LA RECERCA

    Duration: 2022-2024

    Principal Investigator: CUMERAS OLMEDA, RAQUEL

  • Title: Dts21/00113 titol: test de diagnostico colorrectal para un cribado optimo del paciente (coloopt dx)

    Funding entity: INSTITUTO CARLOS III

    Duration: 2022-2025

    Principal Investigator: CUMERAS OLMEDA, RAQUEL

    Investigators: , LOPEZ RUBIO, ROCIO; BALLESTE PERIS, BELEN; CABEZAS MONTERO, INÉS MARÍA; CORREIG BLANCHAR, XAVIER; CUMERAS OLMEDA, RAQUEL; DÍAZ FERNÁNDEZ, MARIA LUISA; GALCERAN PADRÓS, JAUME JOSEP MARIA; GUMA PADRO, JOSEP; MARTINEZ CEREZO, FRANCISCO JOSE; MERINO VARELA, SANDRA; MUÑOZ BOZA, FELIX; QUER BONIQUET, JUAN CARLOS; RIU FERRANDO, FRANCISCO PEDRO; ROIG BOURGINE, BARBARA; SANS MATEU, Mª TERESA

Membres De L’equip

  • Responsable de grup

    • Xavier Correig Blanchar

  • Investigador sènior

    • Esteban Del Castillo Pérez
    • Nicolau Cañellas Alberich
    • Oscar Yanes Torrado
    • Jesús Brezmes Llecha
    • Noelia Ramírez González
    • Maria Vinaixa Crevillent
    • Raquel Cumeras
    • Pere Ràfols Soler

  • Tècnic/a

    • Laura Massó Estradé
    • Miriam Navarro Sanz
    • Josep Mª Badia Aparicio
    • Pineda Molas Porqueras

  • Investigador/a Post-doctoral

    • Jordi Capellades Tomàs
    • María García-Altares Pérez

  • Doctorant

    • Maria Llambrich Rodriguez
    • Lluc Sementé Fernández
    • Gerard Baquer Gómez
    • Sònia Torres
    • Alexandra Iakab
    • Carla-Melissa Merino
    • Joan Miró

  • Estudiant en pràctiques

    • Roger Giné Bertomeu

Altres grups de Nutrició i Metabolisme

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